Look closer: The multidimensional patterns of post-stroke burden behind the modified Rankin Scale

V Rethnam; J Bernhardt; H Johns; KS Hayward; JM Collier; F Ellery; L Gao; M Moodie; H Dewey; GA Donnan; L Churilov

Journal article

Look closer: The multidimensional patterns of post-stroke burden behind the modified Rankin Scale

V Rethnam, J Bernhardt, H Johns, KS Hayward, JM Collier, F Ellery, L Gao, M Moodie, H Dewey, GA Donnan, L Churilov

International Journal of Stroke | SAGE PUBLICATIONS LTD | Published : 2021

DOI: 10.1177/1747493020951941

Abstract

Background: The utility-weighted modified Rankin Scale, representing patient perspectives of quality of life, is a newly proposed measure to improve the interpretability of the modified Rankin Scale. Despite obvious advantages, such weighting imperfectly reflects the multidimensional patterns of post-stroke burden. Aims: To investigate multidimensional patterns of post-stroke burden formed by individual domains of Assessment of Quality of Life and Barthel Index for each modified Rankin Scale category. Methods: In the A Very Early Rehabilitation Trial (n = 2104), modified Rankin Scale scores and modified Rankin Scale-stratified Barthel Index scores of Self-care and Mobility, and Assessment of..

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University of Melbourne Researchers

Julie Bernhardt Author

Hannah Johns Author

Kate Hayward Author

Geoffrey Donnan Author

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Grants

Awarded by National Institute for Health and Care Research

Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: AVERT was funded by National Health and Medical Research Council (NHMRC) of Australia (386201, 1041401); Chest Heart and Stroke Scotland (Res08/A114); Northern Ireland Chest Heart and Stroke (AVERT-NI 2008); Singapore Health (SHF/FG401P/2008); the UK Stroke Association (TSA2009/09); and UK National Institute of Health Research (HTA Project 12/01/16). VR supported by Post-Graduate Scholarship from NHMRC Centre of Research Excellence in Stroke Recovery and Brain Rehabilitation (1077898). NHMRC fellowship funding was provided to KH (1088449), HD (336102) and JB (1058635, 1154904). JB also received fellowship funding from Australian Research Council (0991086) and the National Heart Foundation. The Florey Institute of Neuroscience and Mental Health acknowledges the support of the Victorian Government's Operational Infrastructure Support Grant.